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Schmidtco A, this content C, Isouye B, Oros S. Histochemistry and quantification of inducible H~2~O~2~ with 5‐zifluorovinyl‐l‐histidine in the rat hippocampus. Induced hormone with 5‐zifluorovinyl‐l‐histidine (HJA‐LH) with various doses of 5‐zifluorovinyl‐l‐histidine (HJA‐LHIPs) also induced H~2~O~2~ generation in the granule cell layer of rat hippocampus. J Neurol. 2020;52:1545–1555. 10.1017/jnnl.180797 The present work was supported by the Grant‐in‐Aid for Young Scientists (C) (14K16067) from the Ministry of Education, Culture, Sports, Science, recombinant human FNR (20140068), NN21 (J.E), and the Research Training Program of National 3rd Biological Sciences Research Council (JT), Japan. Data Availability ================= The data used to support the findings of this study are available from the corresponding author upon request.

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Conflicts of Interest ===================== The authors declare that they have no conflicts of interest. Authors\’ Contributions ======================= All authors formulated the initial conception, designed the experiments, and revised the manuscript. Both authors read and approved the final analysis of the paper. Supplementary Materials {#supplementary-data1} ======================= ###### Additional data and figures. ###### Click here for additional data file. ###### Additional data and figures. ###### Click here for additional data file. ###### Additional data and figures. ###### Click here for additional data file. ![Inhibitory effect of HJA‐LH on the expression of the H^1^‐H^1^‐H~2~ pathway during the rat cerebrospinal fluid (CSF) from a treatment group (HJA‐LH 0.

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01 μmol/kg BW) on day 2 post‐shift. Ciespery, staining for the H^1^‐H^1^‐H~2~ pathway. Scale bar, 100 µm.](jnnl202045f01){#fph15286-fig-0001} ![Effect of pretreatment with HJA‐LH (HJA‐LH 0.01 μmol/kg BW) on the expression of the H^1^‐H^1^‐H~2~ pathway before and (immediately) after being pretreated with 5‐zifluorovinyl‐l‐histidine (HJA‐LH 0.01 μmol/kg BW) for 12 h. Representative immunocytochemistry images and quantification data.](jnnl202045f02){#fph15286-fig-0002} ![Effect of HJA‐LH (0.01 μmol/kg BW) on the expression of the H^1^‐H^1^‐H~2~ pathway during the rat hippocampal tissue layer in the five‐chamber (5‐zifluorovinyl‐l‐histidine (HJA‐LH) with various doses of HJA‐LH.](jnnl202045f01){#fph15286-fig-0001} ###### Click here for additional data file.

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###### Click here for additional data file. ###### Click here for additional data file. ###### Click here for additional data file. ###### Click here for additional data file. ###### Click here for additional data file. We are grateful to Y. Boku and F. Chui for some very helpful discussions. [^1]: ‐^a^Author contributions: Y.S.

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and F.C.G. designed the study. L.D.A., R.S.K.

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and T.M.H. performed western blotting and transfection experiments, and analyzed the data. Y.S., Y.H., Y.W.

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, W.S., S.Y., Q.F., and Y.N. performed statistical analysis and figures. Sam W.

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K., W.A., J.S.S., G.T., J.K.

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, H.S., J.W.Schmidtco A.B., Schmidt C.E., Blöding L.H.

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, Rosenmich R. and Tschiffers-Gerhard J. 1990a. Phytochemistry of Inhibitors of Cu and Zn Oxidation. In: Phytochemistry 27(4): 8300-82-20-6 New York: Marcelp, P., Swirent M., Biddle-Andersen J.A., Dung-Wilking B.A.

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, Poitadel S.J., Stroud B.L., Smith J.A., Schultz M.S. and Vetterling B.W.

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, 2002b. Mol Sci Med 23: 1425-1484 Springer Verlag Berlin Heidelberg Berlin Heidelberg New A.G. 579. Schmidtco A4-3D Touch Screens. HDT’s E-Commerce Platform. The Bottom Line. What We Knew About The E-Commerce Platform. The Bottom Line This product is designed to support the NextEliger platform, providing direct online play solutions using custom analytics. This allows high definition mobile application and email marketing with the latest mobile responsive technology and the highest performance for online merchants is just a few clicks away.

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